Friday April 15, Malaga
Friday April 15, Malaga
00.01 - 23.59
WCO-IOF-ESCEO
08.00 - 09.00
NON-SPONSORED SYMPOSIA
Meeting Room 5
Inflammatory arthritis and bone health
Chairperson: ‣ Elaine M. Dennison
‣ Welcome & Introduction Elaine M. Dennison
‣ Gout and bone health Bo Abrahamsen
‣ HIV arthritis and bone health Karen Walker‑Bone
‣ Novel ways of assessing the relationship between inflammatory arthritis and bone Mark H. Edwards
‣ Discussion Elaine M. Dennison
Meeting Room 1
Preventing future fractures: implementing Fracture Liaison Services throughout the UK
Chairperson: ‣ Henry Mace
‣ Model of support for FLS development Henry Mace
‣ Quality improvement Jo Sayer
‣ Socioeconomic costs and benefits Tim Jones
Meeting Room 2
Evaluation of Fracture Risk: beyond DXA and BTMs
Chairperson: ‣ Serge Ferrari
‣ Distal bone microstructure Emmanuel Biver
‣ Circulating bone regulatory proteins (Sost, Rankl, postn, ...) Roland D. Chapurlat
‣ Falls risk assessment Andrea Trombetti
Meeting Room 3
Physical activity in treatment and prevention of osteoporosis
Chairperson: ‣ Mark Lissens
‣ Introduction Mark Lissens
‣ Importance of physical activity in primary, secondary and tertiary prevention of osteoporosis Olivier Bruyère
‣ Can exercise interventions designed to reduce falls improve bone quality Tash Masud
‣ Specific anti-osteoporotic interventions in patients entering various types of rehabilitation programmes Daniel Uebelhart
Meeting Room 4
Bioactive Collagen Peptides for the Maintenance and Improvement of Musculoskeletal Health
Chairperson: ‣ Stephan Scharla
‣ Welcome and introductory presentation Stephan Scharla
‣ Osteoarthritis / Osteoporosis Steffen Oesser
‣ Sarcopenia Daniel König
09.00 - 12.10
Auditorium 1
SCIENTIFIC SESSION I
Chairpersons: ‣ John A. Kanis, ‣ Jean‑Yves Reginster
09.00
Auditorium 1
Plenary Lecture 1
‣ The Qualities of Bone and Fracture Risk Ego Seeman
09.30
Auditorium 1
Oral communications selected from abstracts
09.30
Auditorium 1
OC1
‣ EFFECTS OF ABALOPARATIDE ON VERTEBRAL, NONVERTEBRAL, MAJOR OSTEOPOROTIC AND CLINICAL FRACTURE INCIDENCE IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS: RESULTS OF THE PHASE 3 ACTIVE TRIAL
Presenting author: ‣ L. A. Fitzpatrick
Authors: ‣ P. Miller, ‣ F. Cosman, ‣ D. Black, ‣ E. Lau, ‣ C. A. F. Zerbini, ‣ B. J. Riis, ‣ C. Christiansen, ‣ S. A. Williams, ‣ M.‑Y. Hu, ‣ G. Hattersley
09.40
Auditorium 1
OC2
‣ EIGHTEEN MONTHS OF TREATMENT WITH ABALOPARATIDE FOLLOWED BY SIX MONTHS OF TREATMENT WITH ALENDRONATE IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS: RESULTS OF THE ACTIVEXTEND TRIAL
Presenting author: ‣ S. Ferrari
Authors: ‣ F. Cosman, ‣ P. Miller, ‣ G. Hattersley, ‣ S. A. Williams, ‣ M.‑Y. Hu, ‣ B. J. Riis, ‣ C. Christiansen, ‣ L. A. Fitzpatrick
09.50
Auditorium 1
OC3
‣ SUPERIOR GAINS IN BONE MINERAL DENSITY AND ESTIMATED STRENGTH AT THE HIP FOR ROMOSOZUMAB COMPARED WITH TERIPARATIDE IN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS TRANSITIONING FROM BISPHOSPHONATE THERAPY: RESULTS OF THE PHASE 3 OPEN-LABEL STRUCTURE STUDY
Presenting author: ‣ J. Malouf
Authors: ‣ B. L. Langdahl, ‣ C. Libanati, ‣ D. B. Crittenden, ‣ M. A. Bolognese, ‣ J. P. Brown, ‣ N. S. Daizadeh, ‣ E. Dokoupilova, ‣ K. Engelke, ‣ J. S. Finkelstein, ‣ H. K. Genant, ‣ S. Goemaere, ‣ L. Hyldstrup, ‣ E. Jodar‑Gimeno, ‣ T. Keaveny, ‣ D. L. Kendler, ‣ P. Lakatos, ‣ J. Maddox, ‣ F. E. Massari, ‣ J. F. Molina, ‣ M. R. Ulla, ‣ A. Grauer
10.00
Auditorium 1
OC4
‣ A RANDOMIZED DOUBLE-BLIND STUDY OF DENOSUMAB (DMAB) COMPARED WITH ZOLEDRONIC ACID (ZOL) IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS PREVIOUSLY TREATED WITH ORAL BISPHOSPHONATES
Presenting author: ‣ J. Malouf
Authors: ‣ P. Miller, ‣ N. Pannacciulli, ‣ J. P. Brown, ‣ E. Czerwinski, ‣ B. S. Nedergaard, ‣ M. A. Bolognese, ‣ H. G. Bone, ‣ J.‑Y. Reginster, ‣ A. Singer, ‣ C. Wang, ‣ R. B. Wagman, ‣ S. Cummings
10.10
Auditorium 1
OC5
‣ THE PHASE 3 COMPARISON OF RALOXIFENE AND LASOFOXIFENE (CORAL) TRIAL: CHANGES IN BONE MARKERS AND BONE MINERAL DENSITY
Presenting author: ‣ M. R. McClung
Authors: ‣ J. Symons, ‣ D. Portman
10.20
Auditorium 1
OC6
‣ A RANDOMIZED CONTROLLED TRIAL OF SCREENING IN THE COMMUNITY TO REDUCE FRACTURES IN OLDER WOMEN IN THE UK (THE SCOOP STUDY)
Presenting author: ‣ L. Shepstone
Authors: ‣ E. Lenaghan, ‣ S. Clarke, ‣ R. Fordham, ‣ N. Gittoes, ‣ I. Harvey, ‣ R. Holland, ‣ A. Howe, ‣ T. Marshall, ‣ E. V. McCloskey, ‣ T. J. Peters, ‣ J. A. Kanis, ‣ T. W. O'Neill, ‣ D. Torgerson, ‣ C. Cooper
10.30
Auditorium 1
Plenary Lecture 2
‣ Offset of fracture risk after treatment cessation, a base for transient treatment interruption Eugene McCloskey
11.00
Auditorium 1
Presentation of the ESCEO-MSD Fellowships
‣ Cyrus Cooper, ‣ Anne De Papp
11.10
Auditorium 1
Oral communications selected from abstracts
11.10
Auditorium 1
OC7
‣ EFFECT OF ODANACATIB ON BONE DENSITY AND ESTIMATED BONE STRENGTH IN POSTMENOPAUSAL WOMEN: A CT-BASED SUBSTUDY OF THE PHASE 3 LONG-TERM ODANACATIB FRACTURE TRIAL (LOFT)
Presenting author: ‣ K. Engelke
Authors: ‣ B. L. Langdahl, ‣ T. DeVilliers, ‣ T. Keaveny, ‣ H. K. Genant, ‣ S. Ather, ‣ H. Giezek, ‣ A. Lombardi, ‣ A. Leung, ‣ A. De Papp
11.20
Auditorium 1
OC8
‣ PREVENTING BONE LOSS UPON STOPPING DENOSUMAB THERAPY: FINDINGS FROM TWO CLINICAL STUDIES
Presenting author: ‣ M. R. McClung
Authors: ‣ P. Miller, ‣ D. L. Kendler, ‣ N. Pannacciulli, ‣ A. Wang, ‣ R. B. Wagman, ‣ S. Ferrari
11.30
Auditorium 1
OC9
‣ PRIOR EXPOSURE TO BISPHOSPHONATES PREVENTS THE REBOUND OF BONE TURNOVER MARKERS AFTER DENOSUMAB THERAPY
Presenting author: ‣ B. Uebelhart
Authors: ‣ R. Rizzoli, ‣ S. Ferrari
11.40
Auditorium 1
OC10
‣ EFFECT OF INVESTIGATIONAL TREATMENT ABALOPARATIDE FOR PREVENTION OF MAJOR OSTEOPOROTIC FRACTURE OR ANY FRACTURE IS NOT ALTERED BY BASELINE FRACTURE PROBABILITY
Presenting author: ‣ E. V. McCloskey
Authors: ‣ N. C. Harvey, ‣ A. Odén, ‣ H. Jiang, ‣ S. Modin, ‣ L. A. Fitzpatrick, ‣ J. A. Kanis, ‣ H. Johansson
11.50
Auditorium 1
OC11
‣ BONE’S MICROSTRUCTURE AND MATERIAL COMPOSITION ARE COMPROMISED IN WOMEN SUFFERING ATYPICAL FEMORAL FRACTURES DURING ANTIRESORPTIVE THERAPY
Presenting author: ‣ E. Seeman
Authors: ‣ R. Zebaze, ‣ A. Chiang, ‣ H. Nguyen, ‣ A. Ghasem‑Zadeh, ‣ M. Belen Zanchetta, ‣ J. R. Zanchetta, ‣ P. R. Ebeling
12.00
Auditorium 1
OC12
‣ RISK FOR HIP FRACTURE TEN YEARS BEFORE AND AFTER TOTAL KNEE REPLACEMENT SURGERY IN THE ENTIRE SWEDISH POPULATION
Presenting author: ‣ C. H. Vala
Authors: ‣ J. Kärrholm, ‣ S. Sten, ‣ M. Karlsson, ‣ D. Sundh, ‣ M. Lorentzon, ‣ D. Mellström
12.15 - 13.45
Auditorium 1
INDUSTRY-SPONSORED LUNCH SYMPOSIUM
12.15 - 13.45
Auditorium 2
INDUSTRY-SPONSORED LUNCH SYMPOSIUM
14.00 - 15.00
Poster Area
Poster Viewing Session I (P100-P450)
14.00 - 15.10
Podium
Oral presentation of selected posters
Chairperson: ‣ Johanne Martel‑Pelletier
14.00
Podium
P915
‣ ACCUMULATED QUALITY OF LIFE LOSS 36 MONTHS AFTER VERTEBRAL AND DISTAL FOREARM FRACTURE: RESULTS FROM ICUROS IN LITHUANIA
Presenting author: ‣ M. Tamulaitiene
Authors: ‣ V. Alekna, ‣ F. Borgström, ‣ V. Sinkeviciene, ‣ A. Svedbom, ‣ R. Stukas, ‣ J. A. Kanis
14.07
Podium
P836
‣ VERTEBRAL FRACTURE RISK: ALENDRONATE TREATMENT ENHANCES ANTERIOR MICROSTRUCTURE IN OSTEOPOROTIC VERTEBRAE
Presenting author: ‣ A. vom Scheidt
Authors: ‣ M. Krause, ‣ K. Püschel, ‣ M. Amling, ‣ B. Busse
14.14
Podium
P829
‣ CATHEPSIN K KNOCKOUT IMPROVES BONE MASS AND SUPPRESSES LONG BONE FRACTURES IN THE OSTEOGENESIS IMPERFECTA MOUSE MODEL (OIM)
Presenting author: ‣ T. Roels
Authors: ‣ J.‑P. Devogelaer, ‣ L. T. Duong, ‣ M. Cardinal, ‣ C. Behets, ‣ D.H. Manicourt
14.21
Podium
P822
‣ LOW-COST AND EFFICIENT FINITE ELEMENT ANALYSIS OF BONE FOR HIGH-RESOLUTION PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY DATA
Presenting author: ‣ L. Warren
Authors: ‣ M. H. Edwards, ‣ Z. Au, ‣ K. A. Ward, ‣ E. M. Dennison, ‣ C. Cooper, ‣ P. Schneider
14.28
Podium
P690
‣ IMPACT OF FRACTURE RISK ASSESSMENT TOOLS ON PROPORTIONS OF WOMEN WITHOUT PRIOR FRACTURE IDENTIFIED AT RISK AND TREATED – LESSONS FROM THE SIGN GUIDANCE
Presenting author: ‣ E. V. McCloskey
Authors: ‣ J. E. Compston, ‣ C. Cooper, ‣ N. C. Harvey, ‣ H. Johansson, ‣ A. Odén, ‣ J. A. Kanis
14.35
Podium
P492
‣ POST-FRACTURE CARE: DO WE NEED TO EDUCATE THE PATIENTS RATHER THAN THE DOCTORS? THE PREVOST RANDOMIZED CONTROL TRIAL
Presenting author: ‣ B. Merle
Authors: ‣ R. D. Chapurlat, ‣ E. Vignot, ‣ T. Thomas, ‣ J. Haesebaert, ‣ A.‑M. Schott
14.42
Podium
P373
‣ REBOUND-ASSOCIATED VERTEBRAL FRACTURES AFTER DENOSUMAB DISCONTINUATION: A SERIES OF 8 WOMEN WITH 35 SPONTANEOUS VERTEBRAL FRACTURES.
Presenting author: ‣ O. Lamy
Authors: ‣ D. Stoll, ‣ E. Gonzalez‑Rodriguez, ‣ D. Hans, ‣ B. Aubry‑Rozier
14.49
Podium
P155
‣ HOW DOES THE INITIAL SLOPE OF THE VARIOGRAM, THE TEXTURAL BASIS OF THE TRABECULAR BONE SCORE, PREDICT VERTEBRAL STRENGTH?
Presenting author: ‣ P. K. Zysset
Authors: ‣ G. Maquer, ‣ Y. Lu, ‣ E. Dall'Ara, ‣ X. Chevalier, ‣ M. Krause, ‣ L. Yang, ‣ R. Eastell, ‣ K. Lippuner
14.56
Podium
P148
‣ THE WNT-INACTIVATING LIPASE NOTUM AS A NOVEL ANABOLIC OSTEOPOROSIS DRUG TARGET
Presenting author: ‣ R. Brommage
Authors: ‣ A. Y. Thompson, ‣ M. K. Shadoan, ‣ C. Liu, ‣ S. Jeter‑Jones, ‣ J. Ciu, ‣ D. G. Potter, ‣ D. Bright, ‣ F. Mseeh, ‣ J. P. Bardenhagan, ‣ G. M. Hansen, ‣ P. Vogel, ‣ J. E. Tarver, ‣ B. Zambrowicz, ‣ C. T. Liu, ‣ D. R. Powell
15.03
Podium
P105
‣ THE IMPACT OF VITAMIN D, CALCIUM, PROTEIN SUPPLEMENTATION, AND PHYSICAL EXERCISE ON BONE METABOLISM AFTER BARIATRIC SURGERY: THE BABS STUDY
Presenting author: ‣ H. Resch
Authors: ‣ C. Muschitz, ‣ R. Kocijan, ‣ J. Haschka, ‣ A. Zendeli, ‣ T. Pirker, ‣ G. Muschitz, ‣ P. Pietschmann
14.00 - 15.00
Conference Room 2.2
EDUCATIONAL LECTURE
Conference Room 2.2
The ABC of writing a manuscript
‣ Ego Seeman
14.00 - 15.00
MEET-THE-EXPERT SESSIONS
Meeting Room 4
Effective control of inflammatory arthritis
‣ Tore Kvien
Meeting Room 5
Hand osteoarthritis: imaging and management
‣ Emmanuel Maheu
Meeting Room 1
General management of osteoarthritis patients
‣ Burkhard Leeb
Meeting Room 2
Cancer bone disease
‣ Socrates Papapoulos
Meeting Room 3
Management of glucocorticoid-induced osteoporosis
‣ Karel Pavelka
14.00 - 15.00
ESCEO SYMPOSIA
Auditorium 2
ESCEO algorithm for the treatment of osteoarthritis – From evidence-based medicine to real-life setting
Chairpersons: ‣ Jean‑Pierre Pelletier, ‣ Cyrus Cooper
‣ Welcome address Jean‑Yves Reginster
‣ Efficacy and safety of glucosamine sulfate in the management of osteoarthritis: evidence from real-life setting trials and surveys Jean‑Yves Reginster
‣ Efficacy and safety of oral and topical NSAIDs plus analgesics in the management of osteoarthritis: evidence from real-life setting trials and surveys Jean‑Pierre Pelletier
‣ Efficacy and safety of hyaluronic acid in the management of osteoarthritis: evidence from real-life setting trials and surveys François Rannou
‣ Discussion leaders Olivier Bruyère, Jaime Branco
‣ Wrap-up and conclusions Cyrus Cooper
Panel: ‣ Jaime Branco, ‣ Maria Luisa Brandi, ‣ Olivier Bruyère, ‣ Cyrus Cooper, ‣ John A. Kanis, ‣ Tore Kvien, ‣ Emmanuel Maheu, ‣ Johanne Martel‑Pelletier, ‣ Jean‑Pierre Pelletier, ‣ François Rannou, ‣ Jean‑Yves Reginster, ‣ René Rizzoli
Conference Room 2.1
Critical analysis of currently available orthopaedic procedures to increase bone mass, structure and strength through intra-osseous interventions
Chairpersons: ‣ Andreas Kurth, ‣ Dominique Pioletti
‣ Welcome and scope of the problem Serge Ferrari
‣ Current and new tools to assess hip bone strength Philippe K. Zysset
‣ Challenges and opportunities for drug therapies in preventing hip fractures Serge Ferrari
‣ Currently available orthopaedic procedures for bone enhancement Andreas Kurth
‣ Discussion - Leader Maria Luisa Brandi
‣ Wrap-up Serge Ferrari
‣ Adjournment of the meeting John A. Kanis
Panel: ‣ Maria Luisa Brandi, ‣ Serge Ferrari, ‣ John A. Kanis, ‣ Andreas Kurth, ‣ Andrea Laslop, ‣ Socrates Papapoulos, ‣ Dominique Pioletti, ‣ Jean‑Yves Reginster, ‣ René Rizzoli, ‣ Philippe K. Zysset
15.00 - 17.00
Auditorium 1
SCIENTIFIC SESSION II
Chairpersons: ‣ Maria Luisa Brandi, ‣ René Rizzoli
15.00
Auditorium 1
Plenary Lecture 3
‣ Successful musculoskeletal ageing Jonathan D. Adachi
15.30
Auditorium 1
Presentation of the IOF President's Awards
‣ John A. Kanis
15.40
Auditorium 1
Oral communications selected from abstracts
15.40
Auditorium 1
OC13
‣ CORTICAL POROSITY IDENTIFIES WOMEN WITHOUT OSTEOPOROSIS SUFFERING FRAGILITY FRACTURES: THE PROSPECTIVE OFELY STUDY
Presenting author: ‣ S. Boutroy
Authors: ‣ R. Zebaze, ‣ E. Sornay‑Rendu, ‣ E. Seeman, ‣ R. D. Chapurlat
15.50
Auditorium 1
OC14
‣ BONE MATERIAL STRENGTH INDEX IN PATIENTS WITH LOW BONE MASS AND FRAGILITY FRACTURES
Presenting author: ‣ F. Malgo
Authors: ‣ S. Papapoulos, ‣ N. A. T. Hamdy, ‣ N. M. Appelman‑Dijkstra
16.00
Auditorium 1
OC15
‣ RISK AND PREDICTORS OF SUBSEQUENT FRACTURES AFTER AN ATYPICAL FEMORAL FRACTURE
Presenting author: ‣ E. Biver
Authors: ‣ M.‑C. Audet, ‣ R. Peter, ‣ C. R. Meier, ‣ D. Uebelhart, ‣ T. Chevalley, ‣ K. I. Lorenzini, ‣ R. Rizzoli, ‣ S. Ferrari
16.10
Auditorium 1
OC16
‣ LONGITUDINAL CHANGES IN BONE STRUCTURE AS ASSESSED BY PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY AND RELATIONSHIPS WITH MUSCLE HEALTH IN OLDER MEN AND WOMEN
Presenting author: ‣ M. H. Edwards
Authors: ‣ K. A. Ward, ‣ K. A. Jameson, ‣ E. M. Dennison, ‣ C. Cooper
16.20
Auditorium 1
OC17
‣ RELATIONSHIP BETWEEN TOTAL HIP BMD T-SCORE AND INCIDENCE OF NONVERTEBRAL FRACTURE WITH UP TO 10 YEARS OF DENOSUMAB (DMAB) TREATMENT
Presenting author: ‣ S. Ferrari
Authors: ‣ S. Adami, ‣ J. P. Brown, ‣ F. Cosman, ‣ E. Czerwinski, ‣ L. H. De Gregório, ‣ J. Malouf, ‣ J.‑Y. Reginster, ‣ N. S. Daizadeh, ‣ A. Wang, ‣ R. B. Wagman, ‣ E. M. Lewiecki
16.30
Auditorium 1
Plenary Lecture 4
‣ Clinical guidelines for the management of osteoarthritis Cyrus Cooper
17.00 - 18.30
Auditorium 1
INDUSTRY-SPONSORED SATELLITE SYMPOSIUM
17.00 - 18.30
Auditorium 2
INDUSTRY-SPONSORED SATELLITE SYMPOSIUM